After decent rally, perhaps time for a pause

NEW YORK (Reuters) - Stocks could struggle to extend their seven-week winning streak as the quarterly earnings period draws to a close and the market bumps into strong technical resistance.

Many analysts say the market could spend the next few weeks consolidating gains that have lifted the benchmark Standard & Poor's 500 <.spx> by 6.6 percent since the start of the year.

The S&P 500 ended up 0.1 percent for the week, recovering from a late sell-off on Friday after a Bloomberg report about slow February sales at Wal-Mart triggered a slide in the retailer's shares. It was the index's seventh week of gains.

Odds of a pullback are increasing, with the market in slightly overbought territory, said Bruce Zaro, chief technical strategist at Delta Global Asset Management in Boston.

"I do suspect the closing of the earnings season will lead to at least a pause and possibly a pullback," Zaro said. The S&P 500 could shave 3 to 5 percent between now and early April, he said.

Fourth-quarter earnings have mostly beaten expectations. Year-over-year profit growth for S&P 500 companies is now estimated at 5.6 percent, up from a January 1 forecast for 2.9 percent growth, and 70 percent of companies are exceeding analyst profit expectations, above the 62 percent long-term average, according to Thomson Reuters data.

On Thursday, Wal-Mart, the world's largest retailer, is due to report results, unofficially closing out the earnings period. Investors will be keen to see its quarterly numbers, especially after the Friday's news report that rattled investors.

The S&P 500 has gained 4.3 percent since Alcoa kicked off the earnings season on January 8.

The approaching March 1 deadline for across-the-board federal budget cuts unless Congress reaches a compromise adds another reason for caution, especially with recent economic data indicating the recovery remains bumpy.

Manufacturing output fell 0.4 percent last month, the Federal Reserve said on Friday, but production in November and December was much stronger than previously thought.

TESTING RESISTANCE

The S&P 500 has been trading near five-year highs, and it notched its highest level since November 2007 this week. But the gains have pushed the benchmark index almost as far as it is likely to go in the near term, with strong resistance hovering around 1,525 and 1,540, one analyst said.

As a result, the index is set to move sideways, said Dave Chojnacki, market technician at Street One Financial in Huntington Valley, Pennsylvania. "We just don't have the volume or the catalyst right now" to go above those levels, he said.

At the same time, other analysts say, the market has not shown significant signs of slowing, including a break below 15- and 30-day moving averages.

Such moves would be needed to show that momentum is slowing or that the market is at risk of a correction, said Todd Salamone, director of research for Schaeffer's Investment Research in Cincinnati, Ohio. The S&P 500's 14-day moving average is at 1,511 while the 30-day is at 1,494. The index closed Friday at 1,519.

Recent M&A activity, including news this week of a merger between American Airlines and US Airways Group , helped provide some strength for the market this week and optimism that more deals may be on the way.

In the coming days, the market will focus on minutes from the latest Federal Reserve meeting, due to be released on Wednesday, which could provide support if they suggest the Fed will remain on its current course of aggressive monetary easing.

The Fed minutes released in January spooked markets a bit when they revealed that some Fed officials thought it would be appropriate to consider ending asset purchases later in 2013. U.S. Treasury yields rose on that news, though market worries about a near-term end to quantitative easing have since faded.

Among other companies expected to report earnings next week are Nordstrom , Hewlett-Packard and Marriott International

(Reporting By Caroline Valetkevitch; Editing by Leslie Adler)

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Meteor Fragments Rain Down on Siberia; Hundreds of Injuries Reported

MOSCOW — Gym class came to a halt inside the Chelyabinsk Railway Institute, and students gathered around the window, gazing at the fat white contrail that arced its way across the morning sky. A missile? A comet? A few quiet moments passed. And then, with incredible force, the windows blew in.

The scenes from Chelyabinsk, rocked by an intense shock wave when a meteor hit the Earth’s atmosphere Friday morning, offer a glimpse of an apocalyptic scenario that many have walked through mentally, and Hollywood has popularized, but scientists say has never before injured so many people.

Students at the institute crammed through a staircase thickly blanketed with glass and from there out to the street, where hundreds of people were standing in awe, looking at the sky. The flash had come in blinding white, so bright that the vivid shadows of buildings slid swiftly and sickeningly across the ground. The light burst yellow, then orange. And then there was the sound of frightened, confused people.

Around 1,200 people, 200 of them children, were injured, mostly by glass that exploded into schools and workplaces, according to Russia’s Interior Ministry. Others suffered skull trauma and broken bones. No deaths were reported. A city administrator in Chelyabinsk said that more than a million square feet of glass had been shattered by the shock wave, leaving many buildings exposed to icy cold.

And as scientists tried to piece together the chain of events that led to Friday’s disaster — on the very day a small asteroid passed close to Earth — residents of Chelyabinsk were left to grapple with memories that seemed to belong in science fiction.

“I opened the window from surprise — there was such heat coming in, as if it were summer in the yard, and then I watched as the flash flew by and turned into a dot somewhere over the forest,” wrote Darya Frenn, a blogger. “And in several seconds there was an explosion of such force that the window flew in along with its frame, the monitor fell, and everything that was on the desk.”

“God forbid you should ever have to experience anything like this,” she wrote.

At 9 a.m., the sun had just risen on the Ural Mountains, which form a ridge between European Russia and the vast stretch of Siberia to the east. The area around Chelyabinsk is a constellation of defense-manufacturing cities, including some devoted to developing and producing nuclear weapons. The factory towns are separated by great expanses of uninhabited forest.

As residents of Chelyabinsk began their day on Friday, a 10-ton meteor around 10 feet in diameter was hurtling toward the earth at a speed of about 10 to 12 miles per second, experts from the Russian Academy of Sciences reported in a statement released Friday. Scientists believe the meteor exploded upon hitting the lower atmosphere and disintegrated at an altitude of about 20 to 30 miles above the Earth’s surface — not an especially unusual event, the statement said.

This meteor was unusual because its material was so hard — it may have been made of iron, the statement said — which allowed some small fragments, or meteorites, perhaps 5 percent of the meteor’s mass, to reach the Earth’s surface. Nothing similar has been recorded in Russian territory since 2002, the statement said.

Estimates of the meteor’s size varied considerably. Peter Brown, director of the Center for Planetary Science and Exploration at Canada’s Western University, said it was closer to 50 feet in diameter and probably weighed around 7,000 tons. He said the energy released by the explosion was equivalent to 300 kilotons of TNT, making it the largest recorded since the 1908 Tunguska explosion in Siberia, which is believed to have been caused by an asteroid.

Meteors typically cause sonic booms when they enter the Earth’s atmosphere, and the one that occurred over Chelyabinsk was forceful enough to shatter dishes and televisions in people’s homes. Car alarms were triggered for miles around, and the roof of a zinc factory partially collapsed. Video clips, uploaded by the hundreds starting early Friday morning, showed ordinary mornings interrupted by a blinding flash and the sound of shattering glass.

Maria Polyakova, 25, head of reception at the Park-City Hotel in Chelyabinsk, said it was the light that caught her eye.

“I saw a flash in the window, turned toward it and saw a burning cloud, which was surrounded by smoke and was going downward — it reminded me of what you see after an explosion,” she said. The blast that followed was forceful enough to shatter the heavy automatic glass doors on the hotel’s first floor, as well as many windows on the floor above, she said.

Valentina Nikolayeva, a teacher in Chelyabinsk, described it as “an unreal light” that filled all the classrooms on one side of School No. 15.

“It was a light which never happens in life, it happens probably only in the end of the world,” she said in a clip posted on a news portal, LifeNews.ru. She said she saw a vapor trail, like one that appears after an airplane, only dozens of times bigger. “The light was coming from there. Then the light went out and the trail began to change. The changes were taking place within it, like in the clouds, because of the wind. It began to shrink and then, a minute later, an explosion.”

“A shock wave,” she said. “It was not clear what it was but we were deafened at that moment. The window glass flew.”

The strange light had drawn many to the windows, the single most dangerous place to be. Tyoma Chebalkin, a student at Southern Urals State University, said that the shock wave traveled from the western side the city, and that anyone standing close to windows — security guards at their posts, for instance — was caught in a hail of broken glass.

He spoke to Vozhd.info, an online news portal, four hours after the explosion, when cellphones, which had been knocked out, were still out of order. He said that traffic was at a standstill in the city center, and that everyone he could see was trying to place calls. He said he saw no signs of panic.

In those strange hours, Ms. Frenn, the blogger, wrote down the thoughts that had raced through her mind — radiation, a plane crash, the beginning of a war — and noted that her extremities went numb while she was waiting to hear that the members of her family were unhurt.

When emergency officials announced that what had occurred was a meteor, what occurred to her was: It could happen again.

“I am at home, whole and alive,” she wrote. “I have gathered together my documents and clothes. And a carrier for the cats. Just in case.”

Viktor Klimenko contributed reporting from Moscow, Alan Cowell from London and Rick Gladstone from New York.

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Microsoft’s refusal to bring Office to iPad costing it an estimated $2.5 billion a year

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It's a Girl for Bryan Adams

Mom & Babies
Celebrity Baby Blog

02/14/2013 at 06:00 PM ET

Courtesy Bryan Adams

Bryan Adams is in heaven — again!

“Bryan Adams and Alicia Grimaldi welcomed their second baby girl in London earlier this week,” Adam’s rep tells PEOPLE exclusively.

The rocker and Grimaldi, who cofounded his charitable foundation, named their new bundle of joy Lula Rosylea. She joins big sister Bunny, 22 months.

“Lula Rosylea decided to arrive at tea time,” Adams tells PEOPLE. “Rosylea is cockney rhyming slang in London for ‘cup of tea’ and the name Lula comes from Gene Vincent‘s song ‘Be-Bop-A-Lula.’”

The two-time dad’s latest project is his photography book, Exposed.

– Marisa Laudadio

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Study: Fish in drug-tainted water suffer reaction

BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.

It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.

The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.

"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.

Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.

"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."

Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.

They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.

The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.

The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.

The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.

The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.

"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."

Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.

Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.

It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.

Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."

Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.

The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.

Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.

Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.

___

Online:

Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html

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Wall Street ends slightly higher, helped by acquisitions

NEW YORK (Reuters) - The S&P 500 eked out a small gain for a third straight session on Thursday, helped by a flurry of merger activity, though investors see no catalysts to lift the market further with major averages near multi-year highs.

The market's slowed advance took the S&P 500 to its highest intraday level since November 2007 on Wednesday. While the index notched its third straight day of gains, none was more than 0.2 percent.

Shares of H.J. Heinz Co jumped 20 percent to $72.50 after it said Warren Buffett's Berkshire Hathaway and 3G Capital will buy the food company for $72.50 a share, or $28 billion including debt. Berkshire's class B shares rose 1.3 percent to $99.21.

Also supporting the market was data showing the number of Americans filing new claims for unemployment benefits fell more than expected in the latest week. The CBOE Volatility index <.vix> fell 2.4 percent, dropping to 12.67.

"While I'm not bearish, I don't see many upside motivations at these levels," said Donald Selkin, chief market strategist at National Securities in New York, who cited the low level of the VIX as a sign the market was overbought.

Equities have struggled to break above current levels where they have been hovering for almost two weeks. The S&P 500 is up more than 6 percent so far this year.

"We need to digest some of our gains to go higher, but people are so eager to buy on the dips that we're not even seeing dips anymore. People are just chasing the market higher," said Selkin, who helps oversee about $3 billion in assets.

Stocks fell earlier after a report the euro zone's gross domestic product contracted by the steepest amount since the first quarter of 2009. In addition, Japan's GDP shrank 0.1 percent in the fourth quarter, crushing expectations of a modest return to growth.

The Dow Jones industrial average <.dji> was down 9.52 points, or 0.07 percent, at 13,973.39. The Standard & Poor's 500 Index <.spx> was up 1.05 points, or 0.07 percent, at 1,521.38. The Nasdaq Composite Index <.ixic> was up 1.78 points, or 0.06 percent, at 3,198.66.

Constellation Brands soared 37 percent to $43.75 after AB InBev's deal to take over Mexican brewer Grupo Modelo was revised to grant Constellation perpetual rights to distribute Corona and other Modelo brands in the United States. U.S. shares of AB InBev gained 5.1 percent to $92.77.

American Airlines and US Airways Group said they plan to merge in a deal that will form the world's biggest air carrier, with an equity valuation of about $11 billion. US Airways shares fell 4.6 percent to $13.99.

Weakness in Europe contributed to a 5 percent drop in revenue from the region for Cisco Systems , which nonetheless beat estimates as it reported its results late Wednesday. The company's shares dipped 0.7 percent to $20.99.

General Motors Co reported a weaker-than-expected fourth-quarter profit, also citing bigger losses in Europe alongside lower prices in its core North American market. The stock was off 3.3 percent to $27.73.

Only five more stocks rose than fell on the New York Stock Exchange, while 51 percent of Nasdaq-listed shares closed higher.

Volume was light, with about 6.36 billion shares changing hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, below the daily average so far this year of about 6.48 billion shares.

(Editing by Nick Zieminski and Kenneth Barry)

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Benedict Says He Will Be ‘Hidden to the World’ in Retirement

VATICAN CITY — Saying he would soon be “hidden to the world,” Pope Benedict XVI took his leave of parish priests and clergy of the Diocese of Rome on Thursday as he offered personal, and incisive, recollections of the Second Vatican Council, the gathering of bishops 50 years ago that set the Roman Catholic Church’s course for the future.

Benedict, who announced his resignation on Monday in a move that stunned the Roman Catholic world, also indicated that he would not hold a public role once his resignation becomes official on Feb. 28. He is the first pope to step down in nearly 600 years.

“Though I am now retiring to a life of prayer, I will always be close to all of you and I am sure all of you will be close to me, even though I remain hidden to the world,” Benedict, 85 and increasingly frail, told the assembly of hundreds of priests, who had greeted him with a long standing ovation and some tears.

Priests in attendance said they felt they had witnessed a powerful moment in church history, one that also humanized a pope who has often seemed remote. “It moved me to see the pope smile,” said Don Mario Filippa, a priest in Rome. “He has found peace within himself.”

“It was a part of history,” said Father Martin Astudillo, 37, an Argentine priest who is studying in Rome. “This is a man of God who at the end of his public role transmits his vision of the church and relationship with the church,” he added. “We saw in a few words a real synthesis of his vision of the church and what he expects from whomever takes over.”

During the reflection — or “chat” in his words — on the Second Vatican Council, Benedict recalled the “incredible” expectations of the bishops going into the gathering.

“We were full of hope, enthusiasm and also of good will,” he said.

But while the council made landmark decisions that would propel the church into the future, much got lost in the media’s interpretation of what transpired, he said, which led to the “calamities” that have marred recent church history.

The media reduced the proceedings “into a political power struggle between different currents of the church,” and they chose sides that suited their individual vision of the world, the pope said.

These messages, not that of the council, entered into the public sphere and that led in the years to “so many calamities, so many problems, seminaries closed, convents that closed, the liturgy trivialized,” the pope said.

Benedict spoke of how the council had explored ideas of “continuity” between the Old and New Testaments, and of the relationship between the Catholic and Jewish faiths, an issue that was thorny during his tenure.

“Even if it’s clear that the church isn’t responsible for the Shoah, it’s for the most part Christians who did this crime,” Benedict said of the Holocaust, adding that this called for a need to “deepen and renovate the Christian conscience,” even if it’s true that “real believers only fought against” Nazi barbarism.

At a news briefing on Thursday, the Rev. Federico Lombardi, the Vatican spokesman, confirmed a report in the Turin newspaper La Stampa that the pope had accidentally hit his head during a trip to Mexico last March. The press corps traveling with the pope was not informed of the accident.

The Vatican newspaper L’Osservatore Romano has reported that the pope had decided to retire after returning from that trip. But Father Lombardi rejected La Stampa’s suggestion that the episode might have prompted the decision.

La Stampa reported that Benedict had gotten up in the middle of the night but could not find the light switch in the unfamiliar environment, and accidentally hit his head on a bathroom sink.

An unidentified prelate on the same trip said the pope came down to breakfast the next morning with blood in his hair, the paper said. There was also blood on the pillow, “and a few drops on the carpet,” the prelate told La Stampa. “But it was not a deep cut, nor was it worrisome,” and it was covered by the pope’s thick hair, the prelate said. The pope did not complain during the day’s events.

Later that night, the prelate said, he heard that the pope’s doctor had reacted by expressing concerns about so much travel, and that Benedict had responded that he too had concerns about traveling.

Father Lombardi said: “I don’t deny that this episode happened, but it didn’t impact on the rest of his trip, nor on his decision to resign. That isn’t linked to one single episode.”

Since Benedict announced the decision, saying he felt he did not have the strength to continue in his ministry, there has been much closer public scrutiny of his health.

On Tuesday, the Vatican confirmed for the first time that the pope had had a pacemaker since his time as a cardinal and had its batteries changed three months ago.

Once retired, Benedict will live in a convent inside Vatican City, and will be tended to by the nuns who currently look after him. Father Lombardi said Benedict’s longtime personal secretary, Archbishop Georg Gänswein, who was also named prefect of the papal household two months ago, would continue to work for him.

Father Lombardi said he saw no conflict of interest if Archbishop Gänswein served the current pope and his successor.

The prefect is responsible for logistical duties, and “in this sense it is not a profound problem, I think,” Father Lombardi said.

Rachel Donadio contributed reporting.

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Google hits back against BT with patent lawsuits

SAN FRANCISCO (Reuters) – Google Inc and its Motorola Mobility unit struck back on Wednesday against BT Group Plc, filing patent lawsuits against the British telecommunications group more than a year after BT launched its own lawsuit against Google.

BT, Britain’s dominant fixed-line telecoms group, sued Google in 2011 over six patents related to mobile technology. But in a lawsuit filed on Wednesday in a California federal court, Google asserted four patents of its own.

Google spokeswoman Niki Fenwick said the company also filed a separate lawsuit against BT in a U.K. court.

“We have always seen litigation as a last resort, and we work hard to avoid lawsuits,” Fenwick said in an email. “But BT has brought several meritless patent claims against Google and our customers – and they’ve also been arming patent trolls.”

A BT representative said the company does not comment on pending litigation.

BT has accused Google of infringing BT’s mobile patents through numerous products, including the Android mobile platform, Gmail email service and Google Maps. That lawsuit is still pending in a Delaware federal court.

In addition, Google was sued in a Virginia federal court by Suffolk Technologies LLC and one of the patents being asserted by Suffolk was previously owned by BT, according to court filings. A Suffolk attorney declined to comment.

In Google’s U.S. lawsuit, the company said BT violates Google patents that cover technology such as networking and making phone calls over the Internet. Google obtained at least one of the patents in its lawsuit from International Business Machines Corp in 2010, according to a government database.

IBM representatives could not immediately be reached.

The case in U.S. District Court, Central District of California is Google Inc v. BT Americas Inc, BT Conferencing Inc, BT Ins Inc and Ipanema Technologies Corporation.

(Reporting By Alexei Oreskovic and Dan Levine. Editing by Andre Grenon)

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Jada Pinkett Smith Reveals Her 'Craziest' Diet Ever

By Janine Rayford

02/13/2013 at 07:00 PM EST

Jada Pinkett Smith

Ouzounova/Splash News Online

Jada Pinkett Smith knows a thing or two about diet and exercise.

The 41-year-old mom to Jaden, 14, and Willow, 12, who recently showed off an extremely toned beach body, says the craziest diet she's ever done actually involved a whole lot of eating.

"My craziest diet was for The Matrix," Smith told PEOPLE at the Vera Wang Fall 2013 Collection fashion show at Mercedes Benz New York Fashion Week on Tuesday. Seated front row next to model Chrissy Teigen, Pinkett Smith enjoyed some girl time away from husband Will Smith, who recently vacationed with pals – and parents-to-be – Kim Kardashian and Kanye West in Brazil.

To look the part of her butt-kicking character Niobe, the actress was "lifting 170 lbs. chest weight, and a lot of weight on my legs," she said.

While Matthew McConaughey's recent role required the actor to lose 30 lbs., Pinkett Smith says her role called for the opposite.

"I actually had to eat tons and tons and tons of food," Pinkett Smith said. "It was all about building muscle."

These days, the vegetarian eats a lot less, though she admits she still craves "McDonald's French fries."

But don't let her petite frame fool you.

"I love dressing like a tall woman," she said, wearing an on-trend peach dress and sky-high Christian Louboutin heels, "I like a lot of drama in my clothes."

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Clues to why most survived China melamine scandal

WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.

In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?

A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.

The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.

The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.

A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.

Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.

Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.

More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.

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